2-ShareFire
ShareFire is a feature-rich news aggregator that lets you share stories via AIM, Twitter, Facebook, MySpace, email and more with no copying and pasting, or dragging and dropping.
ShareFire lets you read all your news in one place, and share it all in one place, too. With built-in support for over ten different ways to share stories, all you have to do is click on an article to start it cascading through your social network. And it even supports 16 different languages.

3-Tweetr
Tweetr is a twitter client that allows you to send and receive twitter messages but has cool features including.
- Support for taking photos with your webcam
- Sending files, just drag them onto the Tweetr window and it will instantly upload them so you can easily share these files with your friends.


4-Twitch

Automatically updates your timeline | Combines your friends tweets and replies into one stream | Highlighting of replies | Character count and limit | Tiny URL built in to the interface |
Direct Messaging | Supports Hash Tags | Send Photos with TwitPic .

5-Twicker
Twicker is the first (and only) Twitter client that focuses on search.
Its main purpose is to get search results based on your keywords and display them as clickable avatars. When you click on an avatar, Twicker expands to show you the tweet and offer you the option to reply.Of course, you can use it as your primary Twitter client, since it also allows you to send non-reply tweets.

6-Twitulater
Twitulater is an Adobe AIR microblogging client that currently supports Twitter and Koornk. Its aim is to make life easier for power users, who are constantly bombarded by messages from the many people they follow, through automatically splitting the tweet stream into ten different categories based on content rather than whom the messages are from.


7-DestroyTwitter
DestroyTwitter is a robust but compact Twitter application built on the Adobe AIR platform. It consists of a series of canvases that constantly update to keep tweets current and up-to-date using notifications that appear immediately after a new tweet arrives. DestroyTwitter also features complete direct messaging functionality. Messages and tweets can be replied to with the original visible for quick and easy reference.

8-WiURL
WiURL is a great application for shortening any link. It is great for social networks like twitter or pownce.

9-Birdshot
Too busy to keep up with Twitter? Birdshot is a Twitter client stripped down to the basics: send tweets and tell me when I have new responses. We built our app for productive people who need to manage multiple Twitter accounts without getting distracted. Birdshot covers the basics: sending tweets and displaying the total number of recent mentions, replies, and direct messages. Click on any stat to link directly to results on twitter.com.


10-Posty
Posty is a microblogging application which allows interacting with twitter, jaiku, tumblr, friendfeed and identi.ca right from your desktop. It also features browsing of personal/public posts and note replies.
11-Sideline
Sideline is an Adobe® AIR™ application that allows advanced searching and monitoring of the Twitter public timeline.


12-Twhirl
Twhirl is a social software desktop client for services like Twitter, Seesmic, Friendfeed and identi.ca. It allows to connect to multiple account at the same time, keep up with your friends' updates, and share what you are doing .